44′-(45-Dimethyl-12-phenyl­ene)bis­(2-methyl­but-3-yn-2-ol): structural variation in vicinal dialkynols

摘要

The structure of the title compound, C18H22O2, contains two non-equivalent mol­ecules which differ primarily in the location of the –OH groups on opposite sides or on the same side of the mol­ecular plane. Inversion-symmetric pairs of mol­ecules form inter­molecular O—H⋯O hydrogen-bonded tetra­meric synthons that link non-equivalent mol­ecules into an approximately square double layer parallel to (02). Recently reported fluorinated analogues [Kane, Meyers, Yu, Gerken & Etzkorn (2011). Eur. J. Org. Chem. pp. 2969–2980] have significantly different structures of varying complexity that incorporate intra­molecular hydrogen bonding and suggest that further study of structure versus substituents in vicinal dialkynols could be fruitful.