目的 探讨内镜下喷洒卢戈液对早期食管癌及癌前病变的诊断价值.方法 选择2008年1月至2010年12月期间本院门诊及住院食管癌高危患者262例,在常规胃镜检查后进行卢戈碘染色,分别观察并记录染色前后对可疑病变的形态及色泽变化并进行活检.结果 共发现早期癌变病例18例,染色前后内镜发现早期癌灶的病例数分别是5例(2%)和13例(4.9%),染色前、后发现食管黏膜存在中-重度异型增生的患者数分别为4例(1.5%)和33例(13.6%),两者差异有统计学意义(P<0.05).结论 内镜下卢戈碘染色可显著提高早期食管癌及中-重度不典型增生的检出率.%Objective To evaluate the role of Lugol S staining in diagnosing early esophageal cancer. Methods endoscopic exarls were performed in 262 people aged 35 -82 years, who were suspected to have esophageal patho -logical changes. Observing and recording the alternation of color and morphology in mucosa and texture of submucosal blood vessels before and after Lugol S staining. Biopsy was carried out among all people. Results 18 cases of early esophageal cancer,37 cases of moderate an d severe dysplasia diagnosed through biopsy. The diagnosis of early esophageal cancer before and after Lugol S staining were 5(2% ) andl3 (4. 9% ) ; While moderate and severe dysplasia were 4(1. 5% ) and 33 ( 13. 6% ) respectively with significant statistic difference. Conclusions Lugol S staining in endoscopic exam may notably increase the detecting rate of early esophageal cancer, moderate and severe dysplasia.
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