目的：探讨斑秃进展的相关危险因素。方法收集斑秃患者临床资料进行分析，比较同病程下皮肤秃发面积指数与精神因素、伴随症状、家族史、甲状腺自身免疫抗体等的相关性。结果有神经因素与无精神因素患者组间及有伴随症状与无伴随症状患者组间皮肤秃发面积指数差异有统计学意义（t=4.630，5.399，P<0.05），且病程与斑秃进展正相关。有家族史和无家族史的患者组间及有甲状腺自身免疫抗体和无甲状腺自身免疫抗体的患者组间差异无统计学意义（P>0.05）。结论有精神因素或伴随症状的患者斑秃进展较明显。%Objective To investigate the possible risk factors associated with the progression of alopecia areata. Methods Clinical data of patients with alopecia areata were collected for analysis.Comparing the association between the mean skin lesion area index and psychiatric factors, symptoms,family history or the thyroid autoimmune antibody.Results Difference of the mean skin lesion area index between the patients with psychiatric factors or symptoms and those without was statistically significant(t=4.630,5.399,P<0.05). The damage of alopecia areata got more and more severe with the clinical course.Difference of the mean skin lesion area index between the patients with family history or the thyroid autoimmune antibody and those without was no statistically significant.Conclusions The progression of alopecia areata is more than likely to be observed in patients negatively affected by psychiatric factors,symptoms.
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