中西医结合治疗IVF/ICSI-ET过程中OHSS疗效观察

摘要

Objective To observe the therapeutic effect of combined traditional Chinese and Western Medicine on ovarian over stimulation syndrome in IVF/ICSI-ET. Methods The 61 patients of ovarian hyperstimulation syndrome(OHSS),were randomly divided into the observation group(30 cases)and the control group(31 cases). The observation group therapy combined with traditional Chinese medicine decoction on the basis of conventional western medicine treatment,and observe the changes of the symptoms,signs,serum albumin(ALB),fibrinogen(FIB), hematocrit(HCT)of the two groups. Results In the observation group,the total effective rate was 93.3%,the control group was 71%,there was significant difference between the two groups(P<0.05). Two groups of body weight,abdominal circumference significantly than before treatment reduce(P<0.05). The level of each index after treatment in the observation group and the control group at the same time,the differences were statistically significant(P<0.05). HCT,Fib,ALB levels of the two groups of patients after treatment of were compared with those before treatment, the differences were statistically significant(P<0.05). The level of each index in observation group after treatment were compared with the control group at the same time,the differences were statistically significant(P<0.05). Conclusion The combination of traditional Chinese medicine and Western medicine has a significant effect on ovarian hyper stimulation syndrome,and has no adverse reaction.%目的：观察中西医结合治疗IVF/ICSI-ET过程中卵巢过度刺激综合征（OHSS）的疗效。方法 OHSS患者61例，随机分为观察组30例，对照组31例。对照组常规西医治疗；观察组在常规西医治疗基础上加用中药汤剂治疗。同时观察两组患者症状、体征、血浆白蛋白（ALB）、纤维蛋白原（FIB）、红细胞比容（HCT）的变化。结果观察组总有效率为93.3%，对照组为71.0%，两组比较差异有统计学意义（P<0.05）。两组体重、腹围均较治疗前明显降低（P<0.05），观察组与对照组比较，差异均有统计学意义（P<0.05）。两组患者治疗后HCT、Fib、ALB水平与治疗前比较，差异均有统计学意义（P<0.05），观察组治疗后各指标水平与对照组同时间比较，差异均有统计学意义（P<0.05）。结论中西医结合治疗OHSS疗效明显，且无不良反应。