地佐辛在剖宫产术中减轻产妇不适症状的效果观察

摘要

目的：观察地佐辛在剖宫产术中静脉用药减轻产妇不适症状的效果。方法选择40例子宫下段剖宫产的孕产妇，随机分为两组，地佐辛组（Ⅰ组）和对照组（Ⅱ组），记录给地佐辛前（T0），给地佐辛后1min（T1），5 min（T2），10 min（T3），15 min（T4）产妇的心率（HR）、平均动脉压（MAP）、脉搏血氧饱和度（SpO2）值及镇静/警觉评分（OAA/S）；同时观察术中产妇不适症状的发生率。结果两组产妇HR、MAP、SpO2与同组T0比较，各时点值差异无统计学意义（P>0.05），Ⅰ组与Ⅱ组在T2~T3时点比较，MAP值有所下降（P<0.05）。镇静/警觉评分（OAA/S）Ⅰ组的T1、T2、T4时点与Ⅱ组比较略有下降，但差异无统计学意义（P>0.05），T3时点与同组T0及Ⅱ组的T3时点比较，下降明显（P<0.05）。Ⅱ组产妇术中不适症状中恶心3例，剑突下不适6例明显高于Ⅰ组发生率。结论剖宫产术中胎儿取出后辅以小剂量0.1mg/kg地佐辛静脉用药，可明显减少术中不适，提高产妇的舒适感，安全性较高，不良反应少。%ObjectiveTo observe the effect of dezocine in alleviating the uncomfortable symptoms of parturients with cesarean delivery. MethodsForty parturients with cesarean delivery were randomly divided into 2 groups:dezocine group(groupⅠ)and control group(groupⅡ). After fetal childbirth,dezocine group received intravenous dezocine 0.1mg/kg. The heart rate(HR),mean blood pressure(MAP),pulse oxygen saturation(SpO2)and OAA/S score were recorded before dezocine was used(T0),1min(T1),5min(T2),10min(T3),15min(T4) after used. At the same time,the incidence of parturients’ uncomfortable symptoms was also noted.ResultsThere was no significant difference in HR,MAP and SpO2 at each time point compared with T0 in the same group(P>0.05). Compared with groupⅡ,the MAP of groupⅠat T2~T3 was lower(P<0.05). OAA/S score of group I at T1、T2、T4 was slightly lowerthan group II,but there was no significant difference statistically(P>0.05). While there was a significant decline at T3 compared with T0 and T3 of group II(P<0.05). Three parturients in group II felt nausea,six felt discomfort under the xiphoid process. The incidence of uncomfortable symptoms was higher than group I.ConclusionsSmall dose of dezocine(0.1mg/kg)used after fetal childbirth can reduce the maternal’ discomfort significantly,with high safety and little adverse effect.