血清PCT及CRP对产妇并发产褥期感染的临床预判价值

摘要

目的 探讨血清降钙素原(PCT)、C反应蛋白(CRP)联合检测对产妇发生产褥期感染的临床预判价值.方法 回顾性分析2014年1月至2016年12月收治的899例产妇的临床资料.结果 899例产妇中有42例发生产褥感染,其发生率为4.67%.感染组PCT、CRP及白细胞水平均明显高于非感染组(P<0.05).ROC曲线分析显示,PCT、CRP及白细胞对应AUC分别为0.912、0.872和0.664,计算所对应最佳临界值分别为2.25ng/ml、7.05mg/L和11.1×109/L,敏感度分别为88.1%、85.7%和71.4%,特异度分别为87.3%、78.3%和61.9%.结论 PCT及CRP的升高对产妇产褥期发生感染有较大的早期预判价值.%Objective To investigate clinical predictive value of PCT and CRP development of maternal puerperal infections. Methods The clinical data of 899 patients with maternal treated in our hospital from January 2014 to December 2016 were retrospectively analyzed. Results 42 cases of the 899 patients with maternal puerperal infections.,and the incidence was 4.67%. The PCT,CRP and WBC in the infected group were signifi cantly higher than the non-infected group(P<0.05). The ROC curve analysis showed that area under the ROC curve of lipase,PCT,CRP and WBC were 0.912、0.872 and 0.664,their correspondent cut-off value were 2.25ng/ml、7.05mg/L and 11.1×109/L,sensitivity were 88.1%、85.7% and 71.4%, specifi city were 87.3%、78.3% and 61.9%,respectively. Conclusion The elevated abnormally of CRP and PCT has major detective value for the development of maternal puerperal infections.