急性脑梗死患者并发下肢深静脉血栓形成的危险因素及近期临床转归分析

摘要

Objective To investigate the risk factors and the short-term prognosis of deep venous thrombosis of lower limbs(LDVT)in acute cerebral infarction patients.Methods809 cases of patients diagnosed acute cerebral infarction and35 cases of patients associated with LDVT were colected from January2014 to January2017 in our department of neurology. They were divided into control group and LDVT group,the associated risk factors and influence on short-term prognosis were analyzed. Results By multivariate Logistic regression analysis,the differences of D-dimer of blood,NIHSS score,diabetes,hypertension,and age between the two groups were statisticaly significant(P<0.05). Compared with the control group,duration of hospitalization prolonged and hospital costs increased in LDVT group. The mortality in patients of LDVT increased in three months after acute cerebral infarction. The differences were statisticaly significant(P<0.05).ConclusionThe D-dimer of blood,NIHSS score,diabetes, hypertension,and age are risk factors(P<0.05)of LDVT in acute cerebral infarction patients. The risk factors should be intervened in a timely and reasonable manner clinicaly.%目的 探讨急性脑梗死患者并发下肢深静脉血栓形成(LDVT)的危险因素及其近期临床转归.方法 2014年1月至2017年1月急性脑梗死患者809例,根据有无LDVT,分为单纯脑梗死组(非LDVT组)和脑梗死并发LDVT组(LDVT组),分析其危险因素及对患者近期临床转归的影响.结果 经多因素Logistic回归分析,两组间的D-二聚体、NIHSS评分、糖尿病、高血压及年龄差异有统计学意义(P<0.05).与非LDVT组比较,LDVT组的患者住院时间延长,住院费用增加,发病3个月内病死率增加,差异有统计学意义(P<0.05).结论 D-二聚体、NIHSS评分、糖尿病、高血压病及年龄是脑梗死并发LDVT的危险因素,临床上需及时合理对危险因素进行干预.