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卒中后失语患者抑郁相关因素分析

             

摘要

Objective To investigate the incidence of depression and the related factors of depression in aphasia patients after stroke. Methods The depression in aphasia patients after stroke were assessed by Stroke Aphasic Depression Questionnaire-Hospital version. According to the score,the patients were divided into depression group and non-depression group. The differences of stroke type,age,sex,stroke-related vascular risk factors,neurological deficit score at admission,and systolic blood pressure were analyzed. And further logistic regression analysis of depression related factors in patients with aphasia after stroke. Results 61 patients were assessed as depression from 107 cases of post-stroke aphasia patients,the incidence of depression was 57%,of which 76.2% of severe depression. Analysis of depression-related factors in the two groups showed that female, aged, the scores of neurological deficits were significantly higher than in the non-depression group,and the P values were 0.026,0.000,0.000. Further analysis of Logistic showed that women,old age and the high score of neural function impairment in admission was independent risk factors for depression in patients with aphasia after stroke. Conclusion Post-stroke aphasia patients with high incidence of depression,and mostly severe depression. In addition, Patients with aphasia after stroke are prone to depression, especially in female,aged and admitted to hospital with severe neurological deficit symptoms. Therefore,such patients need early screening for depression and timely intervention to improve the prognosis.%目的 探讨卒中后失语患者抑郁发生率及抑郁发生相关因素.方法 由经过培训的医护人员,运用医院版卒中后失语患者抑郁问卷对卒中后失语患者进行测评,根据评分结果,分为抑郁组和非抑郁组,并分析两组患者在卒中类型、年龄、性别、卒中相关血管危险因素、入院时神经功能缺损评分、入院时收缩压等差异.并进一步Logistic回归分析卒中后失语抑郁相关因素.结果 107例卒中后失语患者中,61例患者评估为抑郁,抑郁发生率57%,其中重度抑郁占76.2%.两组抑郁相关因素分析发现抑郁组患者在女性、高龄、入院时神经功能缺损评分高方面显著高于非抑郁组,P值分别为0.026、0.000、0.000.进一步二分类Logistsic分析发现女性、高龄、入院时神经功能缺损评分高为卒中后失语患者抑郁发生独立危险因素.结论 卒中后失语患者抑郁发生率高,且多为重度抑郁.另外,女性、高龄、入院时神经功能缺损症状较重的卒中后失语患者易于发生抑郁.因此,对于该类患者需早期进行抑郁筛查,及时干预,以改善患者预后.

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