血浆B型利钠肽作为诊断儿科心脏移植受者发生排斥反应的标记物的价值

摘要

We analyzed 211 consecutive plasma B-type natriuretic peptide(BNP) measurements in 59 pediatric heart transplant patients along with echocardiographic and right ventricular endomyocardial biopsy samples. Patients with a biopsy specimen negative for rejection had significantly lower BNP levels than those patients with a biopsy positive(p≤0.04) for rejection. BNP significantly decreased with treatment(p≤0.007). BNP levels in the first year after heart transplantation in all patients were significantly greater than BNP levels after the first year in all patients(p< 0.001).