Aims To evaluate if elevated biochemical marker levels after coronary a rtery b ypass grafting (CABG) correspond to the amount of peri-operatively infarcted my ocardium,quantified by magnetic resonance imaging (MRI) post-oper-atively. Met hods and results A total of 23 patients without evidence of previous myocardial infarction or myocarditis and with normal pre-operative ECG and left ventricula r function and who underwent elective, primary CABG,without any other concomitan t cardiac surgery, were included. Plasma creatinine kinase MB (CKMB) and troponi n I and T were measured on the first, second and fourth post-operative days. Be tween the fourth and ninth post-operative days, cardiac MRI was carried out. In farctions were found in 18 patients. The infarction mass at MRI was numerically largest in patients with transmural infarctions, all of whom had a CK-MB more t han five times the upper normal limit. All three cardiac markers correlated to t he mass of infarction. Conclusion Elevated biochemical markers after CABG corres pond to the amount of peri-operatively infarcted myocardium.
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