首页> 中文期刊> 《世界核心医学期刊文摘:眼科学分册》 >玻璃体内注射曲安奈德治疗视网膜中央静脉阻塞引起的黄斑水肿

玻璃体内注射曲安奈德治疗视网膜中央静脉阻塞引起的黄斑水肿

         

摘要

Purpose: To evaluate treatment of macular oedema due to central retinal vein o cclusion (CRVO) with intravitreal triamcinolone acetonide. Methods: In a prospec tive case series, 13 patients with macular oedema due to non-ischaemic CRVO rec eived an intravitreal injection of 4 mg triamcinolone acetonide. Examination inc luded assessment of best corrected visual acuity (BCVA) for distance and reading , measurement of intraocular pressure (IOP), fluorescein angiography and high re solution imaging by optical coherence tomography, preoperatively and 1 week, 1 m onth, 3, 6 and 9 months postoperatively. Results: Preoperative mean BCVA was 0.9 ±0.4 for distance vision and 1.0±0.3 for reading acuity, respectively. A signi ficant improvement in distance VA (0.5±0.3, p< 0.001) and reading acuity (0.7± 0.3, p=0.03) was observed until 3 months and 6 months, respectively. Mean macula r thickness was significantly reduced until 9 months postoperatively. Conclusion : Intravitreal injection of triamcinolone acetonide led to a significant improve ment in mean VA in patients with macular oedema due to CRVO. However, the signif icant effect was not permanent and persisted for a maximum of 6 months.

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