cqvip:Objective: The aim of this study was to prospectively investigate flash visual evoked potential (VEP) findings and their chronological changes in preterm infa nts with cystic periventricular leukomalacia (PVL) during the early neonatal per iod.Methods: The subjects of this study were 14 preterm infants with cystic PVL. The patients underwent serial cranial ultrasonography and diagnosed as having c ystic PVL. Flash VEPs were diagnosed at least twice within the first 3 weeks of life.Results: All infants had at least one or more flash VEP abnormalities.The m ost common finding was ‘absent VEP’, which was seen in 13 infants (93%). ‘De layed latency’was seen in two infants and ‘abnormal waveform’was seen in one infant.Concerning the chronological changes, all records were abnormal in 4 infa nts, and the other 10 had transient normal VEP findings. Among them, flash VEPs changed from normal to abnormal within 10 days after birth in most cases. Conclu sions:Almost all infants with cystic PVL had abnormal flash VEPs within the firs t 3 weeks of life, but chronological changes of flash VEP findings were seen dur ing the period. Significance:This manuscript may be useful as a reference to the flash VEP sin preterm infants with cystic PVL.
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