cqvip:Quinacrine has been reported as an antiprion agent and proposed as an immedia tely applicable treatment for Creutzfeldt-Jakob disease (CJD). The authors rep ort the results of an open compassionate procedure to which 32 CJD patients had access. In some genotypic subgroups, a slight but nonsignificant increase in sur vival was observed, likely due to biased inclusion of longterm surviving patient s. There was no pathologic evidence of a beneficial effect of quinacrine treatme nt.
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