不同严重度阻塞性睡眠呼吸暂停低通气综合征中年患者的睡眠结构分析

摘要

Objective To detect percentage of sleep stages between different severity of middle age Obstructive Sleep Apnea/Hypopnea Syndrome(OSAHS)and compare percentage of sleep stages in OSAHS with snore and middle age normal sleeping individual.Methods 58 OSAHS patients who were 40~49 years old,would be treated with mandibular advancing oral appliance in department of Orthodontics,Peoples Hospital of Guangxi Zhuang Autonomous Region from 2004-2014 year were se-lected.They included two group:mild to middle severity(≤ 5 events/hour,respiratory apnea/hypopnea index(AHI)<30 events/hour)34 cases,heavy severity [≤ 30 events/hour,respiratory apnea/hypopnea index(AHI)]24cases.Time percentage of sleep stages S1、S2、S3-4、REM(rapid eye movement stage)in whole night sleeping were compared between two group and normal sleeping group with same OSAHS age range in SPSS 13.0.Independent sample T test were doned.Differences of sleep stages be-tween four group were found.Results There arent any significant difference in time percentage of Stages S1、S2、S3-4、REM between two OSAHS groups.S1 time percentage of mild to middle group in the whole night sleeping is lower,S2 is higher and REM of heavy group is lower than normal group.S2 time percentage of heavy group is lower than mild-middle group.Conclusion Rapid-wane and REM sleep stage in OSAHS are shorter comparatively than normal sleep group.The more severity of OSAHS,the more shorter of S2 sleep stage and longer of S1 sleep stage.%目的：探讨不同严重程度的阻塞性睡眠呼吸暂停低通气综合征（OSAHS）中年患者的睡眠结构特点，并与正常人的睡眠结构作比较。方法选取在2004年至2014年间来广西壮族自治区人民医院口腔正畸科拟行口腔矫治器治疗的40～49岁 OSAHS 患者58例，其中轻中度34例，重度24例，分别对这2组患者及睡眠正常人的睡眠结构 S1、S2、S3和快速动眼（REM）分期的百分比作比较，探讨他们的睡眠结构的差异。结果与正常同龄人相比，轻中度 OS-AHS 患者浅度睡眠占睡眠比例较低，中度睡眠较高；重度 OSAHS 患者浅度、快动眼期睡眠百分比较低。重度 OSAHS 患者的中度睡眠（S2期）百分比较轻中度 OSAHS 患者为低。结论OSAHS 患者的快波睡眠及动眼期睡眠与正常同龄人相比相对缩短。随病情加重，中度睡眠相对减少，浅度睡眠增加。