阻塞性睡眠呼吸暂停低通气综合征与心血管病随访研究

摘要

Objective AIM Observation of obstructive sleep apnea hypopnea syndrome(OSAHS)patients with weight loss therapy.Methods Investigation and follow-up home visits formula,the time is 24 years,analyzing OSAHS group and the control group(no OSAHS group), hypertension,coronary heart disease, heart failure,arrhythmias,cardiomyopathy,pulmonary heart disease,degenerative heart valve disease incidence.Results 1 868 cases, male 956 cases,female 912 cases,followed up starting age of 53 ~82(63 ±6)years,of which 598 OSAHS group(32.0%)patients in the control group of 1 270(68.0%)ca-ses.End comparison shows that cardiovascular disease,OSAHS group 582 /598(97.3%)patients in the control group had 932 /1 270(73.4%)cases(P <0.01).Conclusion OSAHS patients the possibility of cardiovascular disease than the general popula-tion,suggesting that OSAHS correlated with cardiovascular disease,is an independent risk factor for cardiovascular disease.%目的：随访阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与心血管疾病的关系。方法通过家访式调查和随访，时间为24年，分析 OSAHS 组和对照组（无 OSAHS 组）高血压病、冠心病、心力衰竭、心律失常、心肌病、肺心病、退行性心瓣膜病发生情况。结果1868例中，男956例，女912例，随访起点年龄53～82（63±6）岁，其中OSAHS 组598（32．0％）例，对照组1270（68．0％）例。终点发生心血管疾病比较显示， OSAHS 组582／598（97．3％）例，对照组发生932／1270（73．4％）例 （P ＜0．01）。结论OSAHS 患者发生心血管疾病可能性较一般人群高，提示OSAHS 与心血管疾病存在相关性，是心血管疾病的独立危险因素。