Prediction of synchronous colorectal cancers by computed tomography in subjects receiving an incomplete colonoscopy:A single-center study

摘要

AIM:To assess the value of computed tomography(CT)for diagnosis of synchronous colorectal cancers(SCRCs)involving incomplete colonoscopy.METHODS:A total of 2123 cases of colorectal cancer(CRC)were reviewed and divided into two groups according to whether a complete or incomplete colonoscopy was performed.CT results and final histological findings were compared to calculate the sensitivity and specificity associated with CT for detection of SCRCs following complete vs incomplete colonoscopy.Factors affecting the CT detection were also analyzed.RESULTS:Three hundred and seventy-four CRC patients underwent incomplete colonoscopy and 1749received complete colonoscopy.Fifty-six cases of SCRCs were identified by CT,and 36 were missed.In the incomplete colonoscopy group,the sensitivity and specificity of CT were 44.8%and 93.6%,respectively.The positive and negative predictive values were 23.6%and 95.0%,respectively.In contrast,the sensitivity and specificity of CT for the complete colonoscopy group were 68.3%and 97.0%,while the positive and negative predictive values were 22.2%and 98.7%,respectively.In both groups,the mean maximum dimension of the concurrent cancers identified in the CT-negative cases was shorter than in the CT-positive cases(incomplete group:P=0.02;complete group:P<0.01)Topographical proximity to synchronous cancers was identified as a risk factor for missed diagnosis(P=0.03).CONCLUSION:CT has limited sensitivity in detecting SCRCs in patients receiving incomplete colonoscopy.Patients with risk factors and negative CT results should be closely examined and monitored.