Background:Ovarian cancer is known to metastasize to the thyroid gland. Despite an incidence of ovarian metastasis to the thyroid of 3-15%,clinical hypothyroidism resulting from such metastasis has not yet been reported. We present a case of metastatic ovarian cancer to the thyroid resulting in clinical hypothyroidism. Case:A 55-year-old woman with recurrent papillary adenocarcinoma of the ovary presented with fatigue,abdominal distention,lymphedema,and depression. Thyroid stimulating hormone was markedly elevated,and thyroid biopsy demonstrated bilateral metastatic ovarian carcinoma. Conclusion:Although uncommon,metastatic disease to the thyroid should be considered when evaluating a patient with advanced ovarian cancer and clinical hypothyroidism.
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