To examine the effect of large- volume retroperitoneal germ cell tumor on nerve fibers required for erection and ejaculation. Design: Retrospective case reports. Setting:Cancer treatment center. Patient(s): Two male patients presenting with loss of ejaculation but preservation of erection.Result(s): Retroperitoneal lymph nodes lie very close to the sympathetic nerve fibers that control ejaculation. Large-volume tumors would encase the sympathetic plexuses at L1 to L3, making ejaculation impossible. Parasympathetic fibers arise from S2 to S4, so they would not be damaged, preserving erection. Conclusion(s): Thorough history taking is important in the investigation of infertility. Presentation with these symptoms requires further investigation at an early stage to exclude retroperitoneal tumor.
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