Objective: To describe the first case of delivery after the transfer of a single blastocyst derived from a vitrified mature human oocyte. Design: Case report. Setting: Private assisted reproduction clinic. Patient(s): A normal 31-year-old woman. Intervention(s): An unsuccessful attempt was made to extract sperm from the patient’s nonobstructive azoospermic husband by testicular sperm extraction. Main Outcome Measure(s): Transfer of single blastocyst derived from vitrified human oocyte and donor sperm. Result(s): A healthy male neonate weighing 3000 g was born. Conclusion(s): Vitrification is a useful method of preserving mature human oocytes and has the advantage of time-effectiveness, simplicity, cost reduction, and no need for devices such as programmable freezers.
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