枫香脂鲜料干燥方式的研究

摘要

Objective:To study and select the drying method of fresh material of Resina Liquidambaris.Methods:The fresh Resina Liquidambaris was dried by 60 ℃ drying method,shade-drying method,freeze-drying method,auxiliary dispersion drying method and distillation drying method.Based on steam distillation-gas chromatography-mass spectrometry ( SD-GC-MS) technology,the difference of volatile components in different dry preparation samples was compared .Combined with the requirements of the Chinese Pharmacopoeia 2015 edition standard for the quality standard of Resina Liquidambaris ,the quality of samples prepared by different drying methods was evaluated.Results:The dried samples by distillation drying method had the most volatile components .The com-position of the volatile components of the samples prepared by different drying methods was quite different .The samples of the dis-tillation drying method met the requirements of the 2015 edition of the Chinese Pharmacopoeia.Conclusion:It is suggested that the distillation drying method is stable and easy to produce ,which is worthy of further research and further promotion.%目的:研究并选定枫香脂鲜料的干燥方式.方法:对枫香脂鲜料分别采用60 ℃烘干法、阴干法、冷冻干燥法、加辅料分散干燥法、蒸馏干燥法5种方法进行干燥,基于水蒸气蒸馏-气质联用( SD-GC-MS)技术,比较不同干燥方法制备样品中挥发性成分的差异,结合《中华人民共和国药典》2015年版标准中对枫香脂质量标准的要求,对不同干燥方法制备的样品质量进行评价.结果:蒸馏干燥样品中挥发性成分种类最多;不同干燥方法制备的样品挥发性成分组成存在较大差异,蒸馏干燥方法样品符合《中华人民共和国药典》2015年版质量标准要求.结论:提示蒸馏干燥方法工艺稳定,易于大生产,值得深入研究和进一步推广.