泻肺利水法对冠心病心力衰竭患者心衰超声指数的影响

摘要

目的:评价泻肺利水法组方的心衰合剂对冠心病心力衰竭患者心衰超声指数的影响.方法:采用随机对照研究,选取2016年11月至2017年12月首都医科大学附属北京中医医院心血管科住院的冠心病HF、心功能NYHA Ⅲ-Ⅳ级患者60例,分为观察组和对照组,每组30例,观察组予西医常规治疗加用心衰合剂,对照组予西医常规治疗.疗程14 d.观察2组患者治疗前后中医证候积分和心衰超声指数积分.结果:治疗后2组患者中医证候积分均较治疗前显著改善(P＜0.05);组间比较,观察组较对照组改善更为显著(P＜0.05).治疗后观察组的心室充盈、左室射血分数、肺动脉收缩压、房室重构、心衰超声指数积分均较治疗前改善(P＜0.05);治疗后对照组的心室充盈、左室射血分数、肺动脉收缩压、心衰超声指数积分较治疗前提高(P＜0.05).治疗后观察组的瓣膜反流、肺动脉收缩压、心衰超声指数较对照组改善更明显(P＜0.05).结论:在西医规范治疗基础上联合使用泻肺利水法组方的心衰合剂,可以改善冠心病心力衰竭患者的中医证候积分,改善患者的心衰超声指数.%Objective:To evaluate the effects of the method of purging lung and draining water on heart failure echocardiography index in patients with heart failure induced by coronary heart disease.Methods:A total of 55 patients with heart failure induced by coronary heart disease in our hospital from November 2016 to December 2017 were randomly divided into two groups ,the treatment group (30 cases,treated with the routine therapy of western medicine and Xinshuai Mixture ) and control group (30 cases,treated with the routine therapy of Western medicine ).The course of treatment was 14 days.Before and after the treatment ,TCM syndrome integral and the heart failure echocardiography index were tested.Results:After treatment,the TCM symptoms integral of the two groups were significantly improved than before treatment (P＜0.05).The improvement in the treatment group was better than the control group (P＜0.05).The ventricular diastolic function ,left ventricular ejection fraction ,pulmonary artery systolic pressure ,at-rioventricular refactoring and heart failure echocardiography index of the observation group were improved than before treatment (P＜0.05).After treatment,the ventricular diastolic function ,left ventricular ejection fraction ,pulmonary artery systolic pressure and heart failure echocardiography index of the control group were improved than before treatment (P＜0.05).After treatment,the val-vular regurgitation,pulmonary artery systolic pressure and heart failure echocardiography index of the observation group improved more significantly compared with the control group ( P＜0.05).Conclusion:On the basis of western medicine convention treat-ment,the method of purging lung and draining water can effectively improve the TCM symptoms and heart failure echocardiography index in patients with heart failure induced by coronary heart disease .