2型糖尿病患者颈动脉斑块形成的危险因素分析

摘要

Objective:To analyze the risk factors of T2DM patients complicated with carotid plaque incidence.Methods:All the patients in the area under a community hospital's jurisdiction were selected,and divided into the plaque group and non-plaque group according to the results of ultrasonic diagnosis,the age,the course,BMI,WHR,ALT,AST,TBIL,BUN,CRE,TC,TG,WBC,PLT,HGB,FPG and HbA1c of the patients in both groups were surveyed,and the connection between different factors and the plaque incidence was analyzed.Results:All 470 patients were included,the single factor analysis suggested that the factors including age,the course,BMI,WHR,ALT,AST,BUN,TC,WBC,PLT,HGB,FPG,HbA1c,LRI,RRI and others were related to carotid plaque (P＜0.05);Logistic regression analysis results demonstrated that age,the course,FPG,HbA1c and the history of hypertension were the independent risk factors of T2DM patients suffering carotid plaque (P＜ 0.05).Conclusion:Age,the course,FPG,HbA1c and the history of hypertension are the risk factors in the course of T2DM patients happening carotid plaque.%目的:分析2型糖尿病(T2DM)合并颈动脉斑块形成的危险因素.方法:筛选某社区医院辖区内所有2型糖尿病患者,根据超声诊断结果分为斑块组和非斑块组,调查2组患者的年龄、病程、体质指数(BMI)、腰臀比(WHR)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、总胆红素(TBIL)、尿素氮(BUN)、肌酐(CRE)、总胆固醇(TC)、甘油三酯(TG)、白细胞(WBC)、血小板(PLT)、血红蛋白(HGB)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)等因素,分析各因素与斑块形成的相关性.结果:共纳入470例患者,单因素分析显示年龄、病程、BMI、WHR、ALT、AST、BUN、TC、WBC、PLT、HGB、FPG、HbA1c、LRI、RRI等因素均与颈动脉斑块有关(P＜0.05);Logistic回归分析结果表明年龄、病程、FPG、HbA1c、高血压病史是T2DM患者发生颈动脉斑块的独立危险因素(P＜0.05).结论:年龄、病程、FPG、HbA1c、高血压病史是T2DM患者形成颈动脉斑块过程的危险因素.