胶原基硬脑膜的研究进展

摘要

胶原基硬脑膜替代材料能够在颅脑手术中用以修复硬脑膜缺损，并有效诱导修复组织和重建硬脑膜。本文综述了异种生物膜、脱细胞真皮基质以及提取胶原三类硬脑膜材料的相关研究和临床应用情况，总结了这些人工硬脑膜的优缺点，展望了硬脑膜替代材料未来的发展趋势和发展方向。%Collagen-based artificial dura matter can be used to repair dural defects during craniocerebral operations, and is beneficial to triggering the reconstruction of the tissue and dura matter. In this paper we briefly overview the research progress and current situation of corresponding clinical application of three types of collagen-based dura matter repair materials, i.e. heterogeneous biomembrane, acellular dermal matrix and extracted collagen materials, and their advantages and disadvantages. Finally, the prospect of development trend of dural repair materials is made.