Raman spectroscopy is an optical technology based on the theory of Raman scattering, which is generally used in the research of medical and biological science. Raman spectroscopy can be used to detect the molecular structures and com-ponents of proteins, lipids, DNA, and other biological molecules, and provide substantial information about molecules. Thus, Raman spectroscopy is generally considered a “molecular fingerprint”, and it has exceptional advantages in medical research. Moreover, this technique can reflect the changes in molecular structures and detect the alterations of chemical constituents in the samples. Raman spectroscopy, given its high sensitivity and specificity in the detection of the biological samples, has been successfully used to detect and diagnose diseases in numerous sites, such as skin, oral mucosa, breast, head, and neck. In this paper, we introduce the application of Raman spectroscopy in stomatology by conducting a review of the literature.%拉曼光谱是根据拉曼散射原理而形成的一项光谱技术，被广泛地应用于医学和生命科学的研究中。拉曼光谱可以检测生物样本中蛋白质、脂质、DNA和其他生物大分子的结构和组成，提供丰富的分子水平信息，被称为“分子指纹”。拉曼光谱可以早期检测出组织中生物大分子结构、成分和含量的改变，灵敏度高且特异性强，方便快速，在疾病的早期诊断中具有较高的优势，被广泛应用于医学研究领域。目前，拉曼光谱技术已经成为临床原位诊断技术的研究热点，在口腔医学领域的应用愈发普及。本文通过复习文献，对拉曼光谱在口腔医学中的应用作一综述。
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