930566 Mesangial proliferative glomeru-lonephritis induced by anti—Thy—1 antibodyand inflammatory mediators.LTU Zhihong(刘志红),et al.Kidney Center,Jinling Hosp,210002,Nanjing.Chin J Nephrol 1993;9(2):95.The Thy—1 antigen is known as the cell sur-face antigen of the mouse thymocyte and is foundto be expressed also on the rat mesangial cellmembrane.A single intravenous administrationof anti—Thy—1 antibody induces mesangiolytiedestruction of the glomerular structure resultingfrom the mesangial proliferation,but it is a self—limited proliferative model and the proliferativechanges of mesangial cell are slight.In order tomake this model useful for studying the mesan-gial proliferative glomerulonephritis in human,
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