口腔黏膜线状IgA大疱性皮病1例

摘要

The male patient is 51 years old.Gingiva on the double side of upper anterior teeth has burst for 2 months,and worsened for 1 week.Pathological examination shows that the angle of squamous epithelial surface coating is not complete,epithelial layer falls off,local subepithelial cracks have formed,and inflammatory cell infiltration like mononuclear cells can be seen under the epithelium.The pathological diagnosis considers it as pemphigoid.DIF shows IgA banded deposition appears in the true epidermal junction,and lgG,C3,lgM are negative.It is diagnosed as linear IgA bullous dermatosis,and should be given combination treatment with glucocorticoid and Sally amine,which can obtain good results.%患者男,51岁.双侧上前牙唇侧牙龈破溃2个月,加重1周.病理诊断为类天疱疮.直接免疫荧光显示真表皮交界处IgA带状沉积,IgG、C3、IgM阴性.确诊为线状IgA大疱性皮病,给予糖皮质激素及沙利度胺联合治疗,取得良好效果.