DMAE⁃CB和NACP改性牙本质粘结剂的粘结性能和抗菌性能研究

摘要

目的 初步评价添加甲基丙烯酰氧乙基-正十六烷基-二甲基氯化铵(DMAE?CB)和无定形纳米磷酸钙(NACP)的粘结剂粘结性能和抗菌性能.方法 将DMAE?CB和NACP按照不同比例添加到商品化牙本质粘接剂中.按比例的不同将实验分成8组,商品化粘结剂作为对照组,用万能材料试验机进行牙本质剪切强度测试,然后进行接触性抑菌实验,研究不同分组粘结剂固化后,对变形链球菌的抗菌活性.结果 对照组剪切强度为(17.96± 3.45)MPa,实验组结果分别为A:(19.25± 2.80)MPa,B:(18.70±2.42)MPa,C:(18.47±2.73)MPa,D:(18.22±2.50)MPa,E:(17.29±4.54)MPa,F:(18.40±2.98)MPa,G:(18.13±4.39)MPa,实验组和对照组剪切强度差异无统计学意义(P=0.993>0.05).接触性抑菌试验的对照组无明显抗菌作用,实验组抗菌单体添加量为1%时具有明显的抗菌作用(P<0.05),当添加量为3%时,抗菌活性进一步增强,但是添加量为4%时,抗菌活性并未明显增加.结论 添加了DMAE?CB和NACP 的粘结剂固化后,不影响粘结强度,且具有良好的抗菌性能.%Objective To make a preliminary evaluation of the adhesive properties and antibacterial properties of methyl methacrylate bound sixteen alkyl two?ammonium chloride(DMAE?CB)and amorphous calcium phosphate(NACP)binder. Methods DMAE?CB and NACP were added to the commercial dentin adhesive according to different proportions. According to the different proportions,the experiment was divided into 8 groups,the commercialization of binder as the control group.The dentin shear strength was tested by uni?versal testing machine,and the bacteriostatic experiment was conducted,the antibacterial activity against Streptococus mutans of differ?ent groups after adhesion was studied. Results The shear strength of control group was(17.96±3.45)MPa, the experimental group were A:(19.25±2.80)MPa,B:(18.70±2.42)MPa,C:(18.47±2.73)MPa,D:(18.22±2.50)MPa,E:(17.29±4.54)MPa,F:(18.40 ±2.98)MPa,G:(18.13±4.39)MPa,through statistical analysis of P=0.993(P>0.05)the shear strength of the experimental group and the control group the difference was statistically significant; the control group in the contact bacteriostatic test had antibacterial effect,the experimental group of antibacterial monomer addition 1% had significant antibacterial effects(P<0.05),when the dosage is 3%,the antibacterial activity was further enhanced, but when the content is 4%, the antibacterial activity did not significantly in?crease.Conclusion After adding DMAE?CB and NACP,the adhesive has no influence on the bond strength and has good antibacterial properties.