Objective: The aim of this study was to evaluate the analgesic effect of high intensity focused ultrasound (HIFU) in patients with advanced pancreatic cancer. Methods: A total of 106 patients with advanced pancreatic cancer accompanied by abdominal pain were treated by HIFU. Pain intensities and quantities of morphine consumption before and after treatment were observed and compared. Results: The average pain intensities before treatment, and at d3, d7 after treatment were 5.80 ± 2.14, 2.73 ± 2.68, 2.45 ± 2.43 respectively (P < 0.01). Fifty-nine cases (55.7%) got to extremely effective, and 29 cases (27.4%) effective. Total efficient rate was 83.0 %. The average quantities of morphine consumption before and after treatment in the patients with grade III pain were 114.9 ± 132.5 mg, 16.8 ± 39.7 mg each person everyday respectively (P < 0.01). Conclusion: HIFU can relieve pain suffered by patients with pancreatic cancer effectively. It is a new adjuvant treatment for pancreatic cancer pain.
展开▼
