利眠贴对失眠患者疗效的临床研究

摘要

Objective The aim of this study was to evaluate the effect of “LI MIAN TIE”on chronic insomnia therapy. Methods A total of 41 volunteers with chronic insomnia were recruited into this study and 30 volunteer finished the 20 days study.Thirty volunteers underwent “LI MIAN TIE”therapy for 20 days,and fulfilled Insomnia Severity Index (ISI),Pitts-burgh Sleep Quality Index (PQSI),Flinders Fatigue Scale (FFS)before “LI MIAN TIE”therapy,in the 7th and 20th days af-ter “LI MIAN TIE”therapy.And all of them fulfilled sleep log very day during this study.Results “LI MIAN TIE”improved ISI[(19.07±5.71)vs.(14.90±5.49)],PQSI [(13.63±4.18)vs.(11.43±4.19)]and FFS[(12.10±5.64)vs.(10.60±4. 74)]after 20 days (all P<0.05)but not 7 days(all P>0.05)therapy when compared to before therapy.Sleep latency[(50.89 ±29.42)min vs.(38.94±18.83)min],episodes of wake after sleep onset[(2.32±1.45)vs.(1.67±1.03)]and time duration of wake of after sleep onset[(69.07±59.34)min vs.(57.34±46.33)min]were decreased significantly after 20 days therapy when compared to before therapy;total sleep time[(309.17±81.45)min vs.(327.55±77.02)min]was increased significantly after 20 days therapy.Conclusion “LI MIAN TIE”can effectively improve insomnia severity,sleep quality in patients with in-somnia.%目的：探讨“利眠贴”对失眠患者的疗效。方法选择41名慢性失眠患者，接受为期20天的“利眠贴”治疗。应用失眠严重程度量表(ISI)、匹兹堡睡眠质量量表(PQSI)、疲劳量表(FFS)和睡眠日记测验“利眠贴”对失眠严重程度、睡眠质量、疲劳及起效时间的效果。结果治疗20天与治疗前比较，失眠严重程度[ISI：(19.07±5.71) vs.(14.90±5.49)]、睡眠质量[PQSI：(13.63±4.18)vs.(11.43±4.19)]、入睡潜伏期[(50.89±29.42)分钟 vs.(38.94±18.83)分钟]、总睡眠时间[(309.17±81.45)分钟 vs.(327.55±77.02)分钟]，入睡后觉醒时间[(69.07±59.34)分钟vs.(57.34±46.33)分钟]、入睡后觉醒次数[(2.32±1.45)次 vs.(1.67±1.03)次]和疲劳程度[FFS：(12.10±5.64)vs.(10.60±4.74)]，差异有统计学意义(P 均<0.05)，但治疗7天与治疗前比较差异无统计学意义(P>0.05))。结论“利眠贴”对慢性失眠患者的失眠严重程度和睡眠质量有改善作用。