482例门诊精神病患者使用药物情况分析

摘要

Objective To understand the clinic use of antipsychotic drugs and mental illness provide reference for clinical ration-al drug use. Methods Random survey in our hospital in 2014 September,November outpatient 482 antipsychotic prescription medica-tion. Results 482 qntipsychotic prescription medication contains a total of 30 kinds of treatment,including treatment of antipsychotic drugs are 9 kinds of 279 prescriptions,accounting for 57. 88% ,the treatment scheme using 2 kinds of antipsychotic drugs have 18 kinds of 197 prescriptions,accounting for 40. 87% ,treatment using 3 kinds of antipsychotic drugs have 3 kinds of 6 prescription,ac-counted for 1. 24% . Antipsychotic drug treatment program ranked in the top 5 were risperidone sulpiride(31. 90% )(13. 98% )of risperidone and clozapine olanzapine(13. 20% )(12. 54% )(11. 93% ),clozapine use rate of the top 5 were risperidone and olanzap-ine(35. 89% )(12. 54% )(18. 67% )of clozapine and sulpiride(15. 35% )paroxetine(8. 71% ). Scheme for single drug use in our hospital for clinical dominant position,atypical antipsychotics were gradually replaced the traditional antipsychotics as first - line drug use. Conclusion The use of antipsychotic drugs in our basic reasonable prescription drug utilization. Atypical antipsychotic drugs has become a clinical choice.%目的：了解门诊精神病患者抗精神病药物的使用情况，为临床合理用药提供参考。方法采用回顾性调查方法调查广东省第三荣军医院2014年9月、11月门诊482张抗精神病药处方用药情况。结果482张处方共涉及30种治疗方案，其中使用一种抗精神病药物的治疗方案有9种，279张（57.88%），使用2种抗精神病药物的治疗方案有18种，197张（40.87%），使用3种抗精神病药物的治疗方案有3种，6张（1.24%）。抗精神病药物治疗方案居前5位的依次是利培酮（31.90%）、舒必利（13.98%）、利培酮+氯氮平（13.20%）、奥氮平（12.54%）、氯氮平（11.93%），使用率居前5位的分别是利培酮（35.89%）、奥氮平（21.37%）、氯氮平（18.67%）、舒必利（15.35%）、帕罗西汀（8.71%）。结论我院门诊抗精神病药物单一用药方案占主导；非典型抗精神病用药已成为临床首选。