两种全麻方式用于小儿先天性唇腭裂修复术的比较

摘要

Objective To compare the intraoperative maintenance and postoperative recovery pattern of depends onsevoflurane inhalation and propofol-remifentanil total intravenous anesthesia in children's primary clect of lip or palate repair.Methods Forty children aged six month ～ six years.were randomly allocated to 2 groups,including group S and group P-R. In group S , the anesthesia was maintained with sevoflurane inhalation and in group P-R , the anesthesia was maintained with intravenous infusion of propofol and remifentanil. The hemodynamics changes were checked at different time point, recovery time from anesthesia, extubation time and postoperative adverse reactions, Such as nausea/vomiting, emergence agitation and respiratory depression. Results The hemodynamics conditions of the two groups were stable. No adverse events happened in both two groups. Conclussion Sevoflurane inhalation and propofol-remifentanil total intravenous anesthesia were equally suitable for children's primary cleft of lip and plate repair.%目的 比较七氟烷吸入麻醉和丙泊酚瑞芬太尼全凭静脉麻醉在小儿先天性唇腭裂修复术对术中维持、术后恢复情况的影响.方法 40例6个月～6岁择期行唇腭裂修复术患儿随机分为两组(n=20):七氟烷吸入麻醉组(S组)和丙泊酚瑞芬太尼全凭静脉麻醉组(P-R组).观察并比较两组患儿诱导前(T0)、插管时(T1)、手术即刻(T2)、手术15min(T3)、手术30min(T4)及清醒拔管(T5)时血流动力学变化;记录自主呼吸恢复时间、清醒及拔管时间,并观察术后恶心、呕吐(PONV)、苏醒期躁动(EA)、呼吸抑制及嗜睡等不良反应.结果 两组患儿术中血流动力学稳定,均无严重不良反应发生.结论 七氟烷吸入麻醉和丙泊酚瑞芬太尼全凭静脉麻醉均适用于小儿先天性唇腭裂修复术.