解脲支原体感染与胎膜早破及其不良妊娠结局的相关性研究

摘要

Objective To probe into the relationships between ureaplasma urealyticum ( UU) infection and adverse preg-nancy outcome of premature rupture of membrane ( PROM).Methods Collection 120 cases with the premature rupture of mem-brane samples,treatment in hospital during 2012 June to 2013 June as the study group,and 120 normal pregnant women of Inpa-tient as as the control group.In this study polymerase chain reaction was used to examine the UU DNA in cervical secretion in stud-y group and control group pregnant women and subsequent pregnancy outcome was investigated.Results The positive rate of ure-aplasma urealyticum (UU) infection of Premature rupture of membrane(44.76%)was significant higher than those of normal preg-nant women(P<0.05), urealyticum-positive women also had a higher prevalence of premature labor 、incident of fetal distress 、Pneumonia of newborn and the rate of cesarean section than that of urealyticum-negative women ( P<0.05 ).About neonatal as-phyxia was no significant difference between the positive group and the negative group (P>0.05). Conclusion Ureaplasma ure-alyticum ( UU infection in pregnant women with premature rupture of membranes have significant correlation, which may be the im-portant causes of preterm premature rupture of membranes, and may be associated with adverse outcomes in neonates, and increase the rate of cesarean section.%目的探讨宫颈支原体感染与胎膜早破的关系及其对妊娠结局的影响。方法收集我院2012年6月至2013年6月收治的120例胎膜早破孕妇作为观察组，同期收住的120例住院正常待产孕妇作为对照组，对两组对象的宫颈分泌物进行解脲支原体( UU)培养，并对其妊娠结局及新生儿并发症进行分析。结果观察组解脲支原体( UU)感染率(44.76%)高于对照组(11.67%)，差异有统计学意义(P<0.05)。同时解脲支原体(UU)阳性孕妇发生早产、新生儿肺炎、新生儿窘迫及手术产的发生明显增多，差异均有统计学意义(P<0.05)，新生儿窒息发生率观察组高于对照组，但无统计学差异。结论孕妇解脲支原体( UU感染与胎膜早破有明显相关性，可能是导致早产胎膜早破的重要原因，并可能与新生儿不良结局有关，同时增加了剖宫产率。