卒中后抑郁的早期预测及临床对策

摘要

Objective To forecast the early depression after stroke ,and to give early intervention or anti-depressants ,psychological intervention and early nerve function rehabilitation treatment .Methods Eighty patients who may develop post-stoke depression in 130 stoke patients were randomly divided into two group :the study group(40 cases) treated with conventional therapy ,antidepressants ,psychological intervention and daily living ac-tivities training and the control group (40 cases) treated with only conventional therapy.Results After the treat-ment ,nerve function defect scale and Hamilton depression rating scale of the two groups were significantly im-proved ( P<0 .05 or P<0 .01) .And the observation group improved more significantly than control group ( P<0 .05) .Conclusion Early prediction of poststroke depression and early clinical intervention can promote the nerve function rehabilitation in patients ,reduce the incidence of depression after stroke ,and effectively increase the ther-apeutic effect.%目的：对脑卒中后抑郁早期进行预测，并给予早期干预即抗抑郁药、心理干预和早期神经功能康复等治疗。方法将136例脑卒中患者中出现卒中后抑郁的患者80例分为观察组和对照组，对照组（40例）采用常规治疗，观察组（40例）在对照组基础上加抗抑郁药物及心理干预和日常生活能力训练。2组疗程均为12周。结果治疗后2组神经功能缺损评分和汉密尔顿抑郁量表评分均显著改善（ P ＜0．05或 P ＜0．01），但观察组的改善程度较对照组更明显（ P ＜0．05）。结论早期预测卒中后抑郁并给予相应的早期临床干预，能促进患者的神经功能康复和减少卒中后抑郁的发生，有效提高治疗效果。