老年人臂踝脉搏波速度的变化及其相关因素分析

摘要

Objective To investigate the varience and related factors of brachial-ankle pulse wave velocity (baPWV)in the elderly.Methods Nine hundred and sixty five patients 512 male,453 female and average age 65 ± 6 older than 60 years were selected who underwent health check-up from March to December in 2016 in our hos-pital.All subjects were inquired about their body mass index(BMI),blood pressure,resting heart rate,fasting plasma glucose(FPG),triglyceride(TG),total cholesterol(TC),high density lipoprotein(HDL),low density lipoprotein(LDL),baPWV as well as the maximum oxygen uptake(VO2max)were also calculated according to the formula.Participants were grouped according to the baPWV quartile,respectively Q1,Q2,Q3,Q4 four groups. Results The age and TG of Q4 group was higher than those of the other three groups and the level of VO2maxin Q4 group was lower than those of the other three groups.The SBP increased gradually with the increasing of baP-WV.The TC level in Q4 group were higher than that of Q1 and Q3 groups.The baPWV were positively correla-ted with SBP,DBP,BMI,FPG,TG,TC,LDL and age(R =0.678,0.430,0.172,0.222,0.214,0.144,0.145, 0.329,P <0.05)and negative correlated with VO2max(r = -0.122,P <0.05).The SBP,age,BMI,and TG were independent risk factors for baPWV(β=0.675,0.233,-0.107,0.094,P <0.05)showed by further pro-gressive regression analysis.Conclusion SBP,DBP,BMI,FPG,TG,TC,LDL,age,VO2maxwere significantly correlated with the level of baPWV in the elderly and SBP,age,BMI and TG were independent risk factors for baPWV in the elderly.%目的 探讨老年人臂踝脉搏波速度(baPWV)的变化及其相关影响因素.方法 选取2016年3月至10月我院体检的60岁以上老年人965例,其中男性512例,女性453例,年龄(651 ± 6)岁.所有受检者测量体质量指数(BMI)、血压、静息心率,检测空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL),测定baPWV,根据公式计算最大吸氧量(VO2max).结果 将受检者按照baPWV水平四分位分组,分别为Q1、Q2、Q3、Q4组.Q4组年龄高于其余3组,收缩压(SBP)水平随着baPWV水平的增高,逐渐增加.Q4组VO2max水平低于其余3组.Q4组TG高于其他3组,Q4组TC水平高于Q1、Q3组.baP-WV水平与SBP、DBP、BMI、FPG、TG、TC、LDL、年龄呈正相关(r =0.678、0.430、0.172、0.222、0.214、0.144、0.145、0.329,P<0.05),与VO2max呈负相关(r = -0.122,P <0.05).多元逐步回归分析结果显示SBP、年龄、BMI、TG是baPWV水平的独立危险因素(β= 0.675,0.233,-0.107,0.094,P <0.05)结论 SBP、DBP、BMI、FPG、TG、TC、LDL、年龄、VO2max与老年人 baPWV水平明显相关,其中SBP、年龄、BMI、TG是老年人baPWV水平的独立危险因素.