“更眠安汤”治疗肾阴虚型女性更年期失眠的临床疗效

摘要

目的：观察自拟“更眠安汤”治疗肾阴虚型更年期失眠的临床疗效。方法：选择2012年6月至2014年3月以失眠为主诉的女性更年期综合征患者36例，给予“更眠安汤”治疗，4周为1个疗程，共服用2个疗程。采用匹兹堡睡眠质量指数量表和中医证候积分评估患者治疗第4周和第8周时的临床疗效，并进行比较。结果：治疗第4周和第8周时的总有效率分别为86.11%（31/36）和91.67%（33/36），主要睡眠指标较治疗前均有改善，差异有统计学意义(P<0.05)；除夜间多梦指标外，治疗第8周时较第4周的其余睡眠指标均更佳，差异有统计学意义(P<0.05)。结论：“更眠安汤”治疗女性更年期失眠症疗效确切，治疗8周的临床疗效更显著。%Objective:To observe the clinical effect of“Geng Mianan Decoction”in the treatment of menopausal insomnia women with Kidney-Yin deficiency. Methods:Thirty-six patients who complained menopausal insomnia were enrolled in the study between June 2012 and March 2014. As 4-week was a period of treatment, the patients received 2 course of“Geng Mianan Decoction”treatment. The clinical effects of treatment in 4 weeks and 8 weeks were eveluated using TCM symptoms scores and Pittsburgh Sleep Quality Index scores. Results:The total effective rate in 4-week treatment and 8-week treatment was 86.11%(31/36) and 91.67%(33/36)respectively. The sleep indicators were signiifcantly improved after treatment when compared with before. There was a statistical signiifcance (P<0.05). Except for nocturnal dreams indicator, the rest indicators in 8-week treatment were better than those in 4-week treatment with statistical signiifcancer (P<0.05). Conclusion:The“Geng Mianan Decoction”is effective in the treatment of menopausal insomnia. The effect of 8-week treatment is better than 4-wee treatment.