热敏灸热敏化腰阳关治疗坐骨神经痛临床观察

摘要

目的：观察热敏灸热敏化腰阳关治疗坐骨神经痛患者的临床疗效,并初步探讨其作用机制。方法将112例坐骨神经痛患者分为热敏灸热敏化腰阳关组(观察组)、悬灸非热敏化腰阳关组(对照组)及药物组。观察组取热敏化腰阳关,行热敏灸治疗；对照组取非热敏化腰阳关,行悬灸治疗；药物组采用口服腰痹通胶囊治疗。观察3组治疗15 d前后临床症状、疼痛分级指数(PRI)、目测类比分级法(VAS)、现有疼痛强度(PPI)等疼痛量表评分及血清IL-8含量变化情况。结果治疗15 d后,3种治疗方法对坐骨神经痛均有一定治疗作用,观察组疗效最优(P＜0.05)；3组PRI、VAS、PPI疼痛评分及血清IL-8含量均较治疗前降低(P＜0.05),且观察组更低于对照组及药物组(P＜0.05),对照组与药物组比较差异无统计学意义(P＞0.05)。结论热敏灸热敏化腰阳关比悬灸非热敏化腰阳关、口服腰痹通胶囊疗效优,该法为治疗坐骨神经痛较为理想的治疗方法,其机制可能与治疗后病变部位炎症因子降低有关。%ObjectiveTo investigate the clinical efficacy of heat-sensitivepoint Yaoyangguan(GV3)moxibustion for sciatica and preliminarily explore the mechanism of its action.MethodOne hundred and twelve sciatica patients were randomly allocated to heat-sensitive point Yaoyangguan moxibustion (observation), non-heat-sensitive point Yaoyangguan suspended moxibustion (control) and medication groups. The observation group received heat-sensitive point Yaoyangguan moxibustion; the control group, non-heat-sensitive point Yaoyangguan suspended moxibustion; the medication group, oral administration of Yaobitong capsules. The clinical symptoms were scored, the Pain Rating Index (PRI), the Visual Analogue Scale (VAS) and the Present Pain Intensity (PPI) scores were counted and serum IL-8 content was measured in the three groups beforeand after 15 days of treatment.ResultAfter 15 days of treatment, all the three treatments had a certain therapeutic effect on sciatica. The therapeutic effect was bestin the observation group (P<0.05). The PRI, VAS and PPI scores and serum IL-8 contentdecreased in all the three groups compared with before treatment (P<0.05) and were lower in the observation group than in the control and medication groups (P<0.05). There was no statistically significant difference between the control and medication groups (P>0.05).ConclusionHeat-sensitive point Yaoyangguan moxibustion has a better therapeutic effect than non-heat-sensitive point Yaoyangguan suspended moxibustion and oral administration of Yaobitong capsules. This method is an ideal treatment for sciatica. The mechanism may be related to a posttreatment decrease in inflammatory factors in the diseased region.