穴位注射新斯的明对胃肠电图的影响

摘要

Objective To monitor electrogastroenterographic changes after point Fenglong(ST40) injection of neostigmine meth- ylsulfate using an 8-channel electrogastroenterograph and preliminarily explore the time for acupuncture point injection to produce the effect.Methods Ten healthy volunteers were selected as subjects. In the subjects, electrogastroenterogram was recorded using an 8-channel electrogastroenterograph (EGEG) under physiological status for 10 min and at various time points during 50 min after point Fenglong(ST40) injection of neostigmine methylsulfate.Results The average amplitude increased to a small extent immediately after acupuncture point injection and had a gradually obvious increase every 10 min in all leads. There was a statistically significant difference compared with under physiological status in all leads (P<0.05) except the lesser curvature lead (P>0.05). The main power ratio and the percentage of normal slow waves decreased markedly in stomach leads during 30-40 min after acupuncture point injection; there were statistically significant differences compared with under physiological status (P<0.05). There were no statistically significant differences in the changes in intestinal leads (P>0.05).Conclusions The changes in the average amplitude, which indirectly reflects the size of gastric electric power in a certain sense validate the quick promoting effect of point Fenglong(ST40) injection of neostigmine methylsulfate on gastrointestinal motility. It is preliminarily inferred that the time to produce the effect is at about 20 min after acupuncture point injection. The main power ratio and the percentage of normal slow waves decrease markedly in stomach leads after point Fenglong injection, indicating the close correlation of acupoints-meridians-viscera to a certain extent.%目的：通过八导胃肠电图仪监测丰隆穴穴位注射甲硫酸新斯的明注射液前后胃肠电图的变化,初步探索穴位注射的显效时间。方法选取10例健康志愿者应用EGEG八导胃肠电图仪,观察并记录受试者生理状态下10 min及丰隆穴穴位注射甲硫酸新斯的明注射液后50 min内各时间点胃肠电图的变化。结果平均振幅于穴位注射后即开始出现小幅度的增加,注射后20～50 min,各导联每10 min上升逐渐明显,与生理状态下相比,除胃小弯导联外(P＞0.05),其余导联差异均具有统计学意义(P＜0.05)。主功率比和正常慢波百分比在穴位注射后30～40 min之间于胃部导联出现明显降低,与生理状态下相比,差异具有统计学意义(P＜0.05),肠部导联变化显示无显著差异(P＞0.05)。结论在一定意义上间接反映胃电功率大小的平均幅值的变化,验证了丰隆穴穴位注射甲硫酸新斯的明注射液对胃肠运动的促进作用具有速效性,初步推测显效时间约为穴位注射后20 min开始；主功率比和正常慢波百分比在丰隆穴穴位注射后出现胃部导联的的明显降低,在某种程度上说明了腧穴-经络-脏腑的密切相关性。