微卡联合化学药物治疗多耐药结核病临床疗效分析

摘要

Objective:To explore the clinical efficacy of micro card combined with chemical drugs in the treat-ment of multi drug resistant tuberculosis.Methods:80 patients with multi drug resistant tuberculosis I admitted to the unit were randomly divided into chemical group and combination group,40 cases in each group,chemical group received chemotherapy,combined group on the basis of chemical group combined with M.Vaccae treatment,com-pared two groups after the treatment,the sputum negative lesions closed lymphocyte subsets and immune.Results:After treatment,the sputum negative condition and lesion closure in the combined group were better than those in the chemical group(P< 0.05);the serum CD4+ level,CD8+ level and CD4+ /CD8+ level in the combined group were higher than those in the chemical group(P< 0.05).Conclusion:Micro card combined with chemical drugs in the treatment of multi drug resistant tuberculosis curative effect,effectively improve the sputum Mycobacterium tu-berculosis negative,promote the healing of the lesion,improve the patient's own immunity.%目的:探讨微卡联合化学药物治疗多耐药结核病的临床治疗效果.方法:选取收治的多耐药结核病患者80例,随机分为化学组和联合组,每组各40例,化学组单纯给予化学药物治疗,联合组在化学组的基础上联合微卡菌苗治疗,对比两组治疗后痰菌转阴、病灶闭合和免疫淋巴细胞群.结果:治疗后,联合组患者的痰菌转阴情况和病灶闭合情况优于化学组(P<0.05);联合组血清CD4+水平、CD8+水平及CD4+ /CD8+水平均高于化学组(P<0.05).结论:微卡联合化学药物治疗多耐药结核病的疗效确切,有效改善患者痰结核菌转阴,促进病灶愈合,提高患者的自身免疫力.