补肾祛邪法治疗慢性乙型肝炎疗效及对疾病相关指标的影响

摘要

Objective:To investigate the efficacy and effect of nourishing kidney and get rid of evil in the treatment of patients with Chronic hepatitis B on disease related indexes .Methods :102 patients with chronic hepati-tis B admitted in our hospital were divided into the observation group and the control group according to the order of admission and principle of voluntary principle ,and 51 cases in each group .The control group was treated with oral entecavir tablets orally .The observation group was treated with Chinese medicine of nourishing kidney and getting rid of evil ,14 days were as a course of treatment ,and 4 cycles of continuous treatment .Results :The total effective rate of the observation group was 90 .20% and the control group was 70 .59% ,the differences were with statistical significance .Before the treatment ,the liver function indexes between the two groups were with out significant differ-ences .After treatment ,the levels of ALT and AST in the observation group were significantly lower than those in the control group ,and the differences were significant .The liver fibrosis indexes of the two groups before treatment compared ,there were no significant differences .After treatment ,LN ,HA and IV-C in the observation group were significantly lower than those in the control group ,and the differences were with Statistical significance .Conclusion :Nourishing kidney and get rid of evil in the treatment of patients with Chronic hepatitis B ,the clinical treatment is significant than the use of western medicine alone ,it can improve the patient's liver function ,regulatethe changesof liver fibrosis index ,and it is the better treatment in clinical treatment .%目的:探讨补肾祛邪法治疗慢性乙型肝炎患者的疗效及对疾病相关指标的影响.方法:选择102例慢性乙型肝炎患者,按照患者入院先后顺序及自愿原则,将患者分为观察组与对照组,每组51例.对照组患者口服恩替卡韦片口服治疗,观察组患者采用中医补肾祛邪法治疗,14d为1个疗程,连续治疗4个周期.结果:观察组患者临床总有效率为90.20%,对照组临床总有效率为70.59%,两组比较差异有统计学意义;治疗前两组肝功能指标比较无统计学差异性,治疗后观察组ALT、AST与对照组比较均降低,比较差异显著;治疗前两组肝纤维化指标比较无统计学差异性,治疗后观察组LN、HA及IV-C与对照组患者各指标比较均明显降低,比较差异有统计学意义.结论:补肾祛邪法用于治疗慢性乙型肝炎疾病,临床治疗效果比单纯采用西药治疗更加明显,改善了患者的肝功能水平,调节其肝纤维化指标的变化,是临床上治疗效果较好的治疗方式.