The paper analyzes the relationship between geographical location and industrial clustering and innovation of the provincial -level. High - tech enterprises' R & D center in Wenzhou area, as the basis for establishing a geographic -based analysis of the economic model. The conclusions are as follows; First, the industry geographic concentration and ag-glomeration is a dynamic process, a particular area of regional competitive advantage has led to geographic concentration of industries and industrial agglomeration, in turn, industry agglomeration and the geographic concentration of industries would consolidate and enhance the competitive advantage of the region; the second , the geographic concentration of industries and industry agglomeration show a strong positive correlation, they may strengthen the innovation, but innovation is impact-ed relatively small by the two.%通过对温州地区省级高新技术企业研发中心的地理区位、产业集聚及创新的相关分析,并以此为基础建立一个基于经济地理分析的计量模型,研究结论如下；第一,产业的地理集中和产业集聚是一个动态过程,某一地区的区位竞争优势促成了产业的地理集中和产业集聚,反过来,产业的地理集中和产业集聚又巩固和增强了这个地区的竞争优势；第二,产业的地理集中与产业集聚呈现出较强的正相关性,它们可能强化创新,但创新受这两者影响相对较小.
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