消肿利节方治疗急性创伤性膝关节滑膜炎近期临床疗效观察

摘要

[ABSTRACT]Objective:To observe the short-term curative effect of Xiaozhong Lijie Fang(消肿利节方, a prescription for promoting the circulation of blood and relaxing the joints)in the treatment of acute traumatic synovitis of knee joint.Methods:79 cases with acute traumatic synovitis of knee joint were randomly divided into a treatment group(41 cases) and a control group(38 cases).The treatment group was treated with Xiaozhong Lijie Fang,while the control group was orally given diclofenac sodium.The 2 groups were treated for 15 days as a course,and they were observed every 5 days.The curative effect was evaluated and the observation index was analyzed in the two groups.Results:In the treatment group,22 cases were cured,condition of 16 cases was improved,3 cases were not cured,and the total efifciency of was 92.68%;while in the control group,17 cases were cured,condition of 11 cases was improved,10 cases were ineffective,and the total efifciency of was 73.68%. The difference between the 2 groups was statistically signiifcant (P< 0.05).Index comparison and analysis of variance to repeated measurement data in the two groups showed pain(F = 4.91,P = 0.03< 0.05),swelling (F = 1.292,P = 0.01< 0.05) and dysfunction(F = 4.03,P = 0.048< 0.05).It can be considered that the treatment group is better than the control group in relieving pain,swelling and dysfunction(P< 0.05). Conclusion:Xiaozhong Lijie Fang is better than diclofenac sodium sustained release tablets in relieving pain,swelling and dysfunction and has a short-term curative effect.%目的：观察消肿利节方治疗急性创伤性膝关节滑膜炎的近期疗效。方法：将79例膝关节创伤性滑膜炎患者随机分为治疗组41例和对照组38例，治疗组口服消肿利节方，对照组口服双氯芬酸钠。2组均以5 d为1个观察点，15 d为1个疗程，进行疗效评定和观察指标分析。结果：治疗组治愈22例，好转16例，未愈3例，总有效率为92.68%；对照组治愈17例，好转11例，未愈10例，总有效率为73.68%。2组比较，差异有统计学意义（P<0.05）。2组观察指标比较，重复测量资料采用方差分析得出，疼痛（F =4.91，P =0.03<0.05）；肿胀（F =12.92，P =0.01<0.05）；功能障碍（F =4.03， P =0.048<0.05）。可认为治疗组与对照组在改善疼痛、肿胀、功能障碍方面有差异，且治疗组改善优于对照组（P<0.05）。结论：消肿利节方在改善疼痛、肿胀、功能障碍方面优于双氯芬酸钠缓释片，近期疗效确切。