目的:通过分析神经元放电与场电位的相干性,探讨内嗅皮层神经元放电与场电位的关系.方法:10只成年大鼠随机分2组,一组糖尿病建模,另一组作为对照,记录对照组和糖尿病组大鼠的内嗅皮层神经元放电锋电位和场电位,利用点过程谱分析方法对神经元放电与场电位相干性进行分析对比.结果:糖尿病大鼠麻醉神经元放电与场电位的相干性明显低于对照组(P＜0.01).结论:糖尿病大鼠内嗅皮层神经无功能受到损害.%Objective:To evaluate the effects of intra-arterial hyperthermic perfusion chemotherapy for uterine cervical cancer, and to analyze which factor influencing the response to the chemotherapy. Methods: Thirty-four patients with cervical cancer were enrolled in this study. Heating intra-arteray chemothyrapy was performed using cisplatin-based regimens. The response was assessed by ultrasound and examination of surgical specimens. Results: Clinical response was achieved in 28 (82%) patients. Twenty-eight of the 38 parametrial halves were free from cancer. No lymph node metastases were found in eight patients. Initial tumor volume was found to be an independent, significant determining factor of the response to the therapy. Pathological type is another fator which influnce the intervention therapy. Conclusion: Intra-atery hyperthermic perfusion chemotherapy for cervical cancer is useful for the tumor reduction. Tumor volume is a significant determining factor for the response to intra-artery hyperthermic perfusion chemotherapy of uterine cervical cancer
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