达那唑对ITP患者血小板数量的影响

摘要

目的 观察达那唑对血小板减少性紫癜(ITP)患者血小板数量的影响,并探讨其机制.方法 回顾性分析31例ITP患者,以达那唑为主进行治疗,疗程为3个月,并于治疗前、后行血小板计数检测及疗效判定.结果 治疗后,完全反应17例,部分反应7例,微小反应5例,无反应2例,总有效率为93%.患者的血小板数目提升.结论 达那唑治疗ITP的临床疗效满意,能有效提升患者血小板数量.%Objective To observe the effect of danazol on platelet count of thrombocytopenic purpura pa tients, and investigate the mechanism. Methods 31 cases of ITP patients were analyzed retrospectively. The treatment ( main with danazol ) lasted for 3 months,the platelet counts and efficacy were determined. Results After treatment, there were 17 cases of complete response,7 cases of partial response,5 cases of minor response,2 cases without re sponse, the total effective rate was 93 % . The number of platelet was improved. Conclusion The effect of danazol on ITP is good,danazol can effectively increase the number of platelets of ITP patients.