目的 观察绝经后妇女宫腔镜检查治疗中应用复方萘普生栓联合米索前列醇的临床效果.方法 将行宫腔镜检查治疗的144例绝经后妇女随机分为对照组、米索前列醇组、复方萘普生栓组及联合用药组,比较各组术中宫颈扩张度、镇痛效果、人流综合征发生情况及术中出血量.结果 联合用药组术中的宫颈扩张度、人流综合征发生与其他3组相比,差异有统计学意义(P＜0.05),镇痛效果除与复方萘普生组无明显差异外,与其余各组相比,差异有统计学意义(P＜0.05)；各组出血量相比,差异无统计学意义(P＞0.05).结论 米索前列醇与复方萘普生栓联合用于绝经后宫腔镜检查治疗,可使宫颈扩张至理想状态、减轻术中疼痛,降低人流综合征的发生,且不增加术中出血量,值得临床推广.%Objective To observe the clinial effect of the united use of misoprostol and compound naproxen for postmenopausal women before hysteroscopy. Methods 144 postmenopausal women who needed hysteroscopy were randomly divided into control group, misoprostol group, compound naproxen group and combination group, the degree of cervical dilatation,analgesia,the incidence of abortion syndrome,and blood loss in each group were compared. Results Compared with the other three groups, the degree of cervical dilatation in combination group was higher( P < 0. 05 ) , the analgesia was better, the incidence of abortion syndrome was lower, and the blood loss had no increase ( P > 0. 05 ). Conclusion The united use of misoprostol and compound naproxen before hysteroscopy can make cervical dilatation to the ideal state,reduce pain in surgery,reduce the incidence of abortion syndrome without increase of the blood loss, so it is worthy of clinical application.
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