螺旋CT三维重建技术对非小细胞肺癌放射治疗靶区勾画的研究

摘要

目的 研究螺旋CT三维重建技术对非小细胞肺癌放射治疗靶区勾画准确性的影响.方法 应用螺旋CT扫描,图像后处理应用TOMOCON图像融合系统.对肺内病灶分别以常规二维CT及二维CT结合螺旋CT三维重建技术进行肿瘤靶区勾画、体积计算及靶区横径及纵径比较.结果 48例肺癌病人CT定位扫描后常规二维CT靶区勾画结果:靶区体积(GTV)18.85~380.63cm3,中位体积103.60cm3;二维CT结合螺旋CT三维重建勾画结果:靶区体积(GTV)24.05~420.57cm3,中位体积130.55cm3.两组数据经配对t检验,分析结果 P=0.037,有统计学意义.两组勾画结果 显示横径平均差异为(1.5±0.5)mm.纵径平均差异为(3.0±1.5)mm.结论 螺旋CT三维重建技术在肺癌放射治疗靶区勾画中的应用价值是值得肯定的.可以作为常规CT横断面扫描图像勾画的一个有力补充,使得肺癌放射治疗靶区勾画的准确性大大提高.%Objective To study spiral CT three - dimensional reconstruction technique for non - small cell lung cancer radiotherapy target volume delineation of the accuracy. Methods Application of spiral CT scan and TOMOCON image system. In lung lesions of normal two - dimensional CT and respectively by two - dimensional CT combined with spiral CT three - dimensional reconstruction technique target volume. The target volume is calculated and compared longitudinal diameter and size. Results 48 cases of lung cancer patients CT Tumor image: gross tumor volume( 18.85 ～ 380.63 cm3 ),median volume 103.60 cm3 ; Two - dimensional CT combined with spiral CT three - dimensional reconstruction results : target volume( 24.05 ～ 420.57 cm3 ) median volume 130.55 cm3. Two sets of data by matching t test, analysis results P= 0.037. Two groups of results showed that the average diameter difference is 1.5±0.5 mm. Longitudinal diameter difference is 3.0 ± 1.5 mm on average. Conclusions Spiral CT three - dimensional reconstruction technique is advantaged to delineate non - small lung cancer radiotherapy target volume. It is a complement of conventional CT scan in non - small cell lung cancer radiotherapy target volume delineation.