电视胸腔镜辅助下肺叶切除术治疗早期非小细胞肺癌疗效及安全性评价

摘要

目的 探讨电视胸腔镜辅助下肺叶切除术(Video-assisted thoracicsurgery,VATS)治疗早期非小细胞肺癌(NSCLC)的疗效及安全性.方法 118例早期NSCLC患者,按照手术方式分为VATS组64例和常规开胸术组54例,观察两组术中及术后情况、术后化疗情况、并发症发生情况及生存率.结果 VATS组手术时间长于常规开胸术组,出血量及引流量均少于常规开胸术组,引流时间及住院时间均短于常规开胸术组,止痛药使用率低于常规开胸术组(P＜0.05).两组术后化疗情况、并发症发生情况及生存率比较,差异均无统计学意义(P＞0.05).结论 VATS手术治疗早期NSCLC住院时间短,术后恢复快,疗效确切、安全,值得临床推广应用.%Objective To evaluate the clinical effect and safety of video-assisted thoracoscopic lobectomy (VATS) in the treatment of early stage non-small cell lung cancer (NSCLC).Methods One hundred and eighteen patients with early stage NSCLC were divided into VATS group (n =64) and conventional thoracotomy group (n =54) according to the operation approaches.The intraoperative and postoperative conditions,the postoperative chemotherapy,the complications occurrence and survival rate were compared between the two groups.Results the operation time in the VATS group was longer than that in the conventional thoracotomy group.However,the bleeding and drainage were less,and drainage time and hospitalization time were shorter than those in the conventional thoracotomy group.In addition,analgesic use rate in the VATS group was lower that in the conventional thoracotomy group (all P ＜0.05).There was no significant difference in postoperative chemotherapy,complications and survival rate between the two groups (P ＞0.05).Conclusion VATS operation in the treatment of early NSCLC is short,postoperative recovery is fast,and the effect is accurate and safe.It is worthy of clinical application.