超声雾化吸入与氧气驱动雾化吸入治疗儿童咳嗽变异性哮喘的临床疗效对比

摘要

Objective To compare the clinical effect between ultrasonic aerosol inhalation and oxygen drive aerosol in­ halation in treating children with cough variant asthma. Methods From February 2009 to February 2012,96 children with cough variant asthma who need aerosol inhalation treatment were selected in the People's Hospital of Yongfeng County,they were divided into groups A and B according to admission date(odd or even),each of 48 cases. Based on comprehensive treatment,A group given budesonide suspension by oxygen drive aerosol inhalation,B group given budesonide suspension by ultrasonic aerosol inhalation. Both groups treated for 7 days as a course of treatment. Clinical effect,disappeared time of cough,gasp and rale,and incidence of adverse reactions were observed. Results The total effective rate of A group was 95. 8% ,was higher than that of B group of 87. 5% (P < 0. 05);the disappeared time of cough,gasp and rale of A group was shorter than that of B group,respec­ tively(P < 0. 05). The incidence of adverse reactions of A group was 33. 3% ,was lower than that of B group of 81. 2% (P <0. 05). Conclusion Oxygen drive aerosol inhalation has better clinical effect than ultrasonic aerosol inhalation in treating chil­ dren with cough variant asthma,can quickly improve the clinical symptoms and is safe.%目的：对比超声雾化吸入与氧气驱动雾化吸入治疗儿童咳嗽变异性哮喘（CVA）的临床疗效。方法选择2009年2月—2012年2月在永丰县人民医院儿科住院且需要雾化吸入治疗的 CVA 患儿96例，按患儿入院日期单双号分为氧气组和超声组，各48例。在综合治疗基础上，氧气组患儿采用氧气驱动雾化吸入布地奈德混悬液，超声组采用超声雾化吸入布地奈德混悬液，均以7 d 为1个疗程。1个疗程后观察两种患儿临床疗效，记录两组患儿咳嗽、气喘、肺部啰音等主要临床症状消失时间和不良反应发生情况。结果氧气组总有效率为95.8％，高于超声组的87.5％（P ＜0.05）；氧气组咳嗽、气喘及肺部啰音消失时间均短于超声组（ P ＜0.05）。氧气组患儿不良反应发生率为33.3％，低于超声组的81.2％（P ＜0.05）。结论氧气驱动雾化吸入治疗儿童 CVA 的临床疗效优于超声雾化吸入，能快速改善患儿临床症状，且安全性良好。