目的：探讨冠心病患者血清胆红素与低密度脂蛋白胆固醇（ LDL-C）水平的关系。方法选择2013年9月—2014年9月西安交通大学医学院第一附属医院收治的冠心病患者55例作为观察组，另选择同期在西安交通大学医学院第一附属医院进行体检的健康者60例作为对照组。检测两组受检者血清总胆红素、直接胆红素、间接胆红素及LDL-C水平，并分析冠心病患者血清胆红素与LDL-C水平的关系。结果观察组患者血清总胆红素、直接胆红素及间接胆红素水平低于对照组，LDL-C水平高于对照组（ P<0.05）。观察组患者血清总胆红素、直接胆红素、间接胆红素水平与LDL-C水平均呈负相关（r值分别为-0.72、-0.31、-0.41，P<0.05）。结论冠心病患者血清胆红素与LDL-C水平均出现异常改变，且血清LDL-C水平随胆红素水平上升而下降。%Objective To explore the relationship between serum bilirubin and LDL - C levels in patients with coronary heart disease. Methods From September 2013 to September 2014,55 patients with coronary heart disease were selected as observation groups in the First Affiliated Hospital of Xi′an Jiaotong University Medicine School,and 60 healthy cases were selected as control group at the same time. Serum levels total bilirubin,direct bilirubin,indirect bilirubin and LDL-C of the two groups were detected,and the relationship between serum bilirubin and LDL-C levels was analyzed. Results Serum levels total bilirubin,direct bilirubin,indirect bilirubin of observation group were lower than those of control group,that of LDL-C was higher than that of control group ( P <0. 05 ). Serum levels total bilirubin, direct bilirubin, indirect bilirubin of observation group was negatively correlated with serum LDL - C level,respectively( r = -0. 72,-0. 31,-0. 41,P <0. 05). Conclusion The serum bilirubin and LDL-C levels of patients with coronary heart disease are abnormal,and with the increasing of serum LDL-C level,serum bilirubin level decreased.
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