A Novel Regenerated Silk Fibroin-based Hydrogels with Magnetic and Catalytic Activities

摘要

A simple and facile synthetic methodology for fabricating the regenerated silk fibroin(RSF)-based hydrogel which consisted of the in situ generated magnetic ferriferous oxide(Fe_3O_4) was developed. Using the co-precipitation of Fe^(2+) and Fe^(3+) within the RSF-based hydrogel with 90% RSF and 10% HPMC(hydroxypropyl methyl cellulose), the as-prepared RSF/Fe_3O_4 hydrogel not only showed high strength of saturation magnetization, but also exhibited excellent catalytic activities. For example, with the assistant of 3,3′,5,5′-tetramethylbenzidine(TMB), the RSF/Fe_3O_4 hydrogel could detect H_2O_2 at a concentration as low as 1 × 10^(-6) mol·L^(-1). In addition, the catalytic activities were able to be maintained for a long term under various conditions. These findings suggest that the RSF-based materials can be endowed with interesting properties, and have great potential for the applications in the fields of biotechnology and environmental chemistry.