Two kinds of fungicides named dodecyl dimethyl benzyl ammonium chloride(1227 )and Kathon 886 were experimentally tested in the lab individually or mixed use in order to investigate their sterilization rate and compatibility with polymer. Test results indicate that the mixed usage of two agents with the mass ratio of 1∶3 (1227∶Kathon 886)achieves better effect than two kinds of fungi-cides used individually and exhibits a high compatibility with polymer for enhanced oil recovery (EOR), indicating the synergetic effect exists. Under the conditions of no oxygen atmosphere,53 ℃ and 90 day aging,the polymer viscosity retention rate is 64.7%. It is concluded that the composite fungicide can be used as a new type of high-effect fungicide in polymer flooding for tertiary oil recovery process.%考察了十二烷基二甲基苄基氯化铵（1227）、异噻唑啉酮（Kathon 886）两种杀菌剂单独使用、复配使用时的杀菌效果和与聚合物的配伍性。结果表明，1227与异噻唑啉酮按照质量比1∶3复配时的杀菌效果优于两剂单独使用时的效果，且与聚合物相配伍，在除氧、53℃的条件下老化90天，聚合物黏度保留率达到64．7％，该药剂可用作三次采油用新型高效杀菌剂。
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